Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the Registration Statements on Form S-8 (No. 333-275610, No. 333-275609, No. 333‑258908, No. 333-233994, No. 333-222657, No. 333-207206 and No. 333-195624) and Form S-3 (No. 333-268532) of Apyx Medical Corporation of our report dated March 13, 2025, relating to the consolidated financial statements of Apyx Medical Corporation, appearing in this Annual Report on Form 10-K of Apyx Medical Corporation for the year ended December 31, 2024.

/s/ RSM US LLP

Tampa, Florida

March 13, 2025