Subsidiaries

State of Incorporation

Wesbanco, Inc.

West Virginia

Wesbanco Bank, Inc.

West Virginia

Wesbanco Insurance Services, Inc.

West Virginia

Wesbanco Title Agency, LLC

Ohio

THF, Inc.

Pennsylvania

Wesbanco Asset Management, Inc.

Delaware

Wesbanco Community Development Corp.

Ohio

CBSI Development Fund, Inc.

Indiana

AMSCO, Inc.

Pennsylvania

Kentuckiana Real Estate Holdings, LLC

Indiana

Southern Indiana Real Estate Holdings, LLC

Indiana

FAH, LLC

Maryland

WSB Realty, LLC

Maryland

Flagship Acquisitions Trust

Maryland

Wesbanco Properties, Inc.

West Virginia

Wesbanco Securities, Inc.

Ohio

Wesbanco Capital Trust II

Delaware

Wesbanco Capital Statutory Trust III

Connecticut

Wesbanco Capital Trust IV

Delaware

Wesbanco Capital Trust V

Delaware

Wesbanco Capital Trust VI

Delaware

Oak Hill Capital Trust 2

Delaware

Oak Hill Capital Trust 3

Delaware

Oak Hill Capital Trust 4

Delaware

Community Bank Shares (IN) Statutory Trust I

Indiana

Community Bank Shares (IN) Statutory Trust II

Indiana

First Federal Statutory Trust II

Kentucky

CBIN Insurance, Inc.

Nevada