EX-23.1 5 eyconsentexhibit231fy2024.htm EX-23.1 Document
Exhibit 23.1
Consent of Independent Registered Public Accounting Firm


We consent to the incorporation by reference in the following Registration Statements:

1.Registration Statement (Form S-3 No. 333-268222) of 2seventy bio, Inc.,
2.Registration Statement (Form S-8 No. 333-260669) pertaining to the 2021 Stock Option and Incentive Plan and 2021 Employee Stock Purchase Plan of 2seventy bio, Inc.,
3.Registration Statement (Form S-8 No. 333-263853) pertaining to the 2021 Stock Option and Incentive Plan and 2021 Employee Stock Purchase Plan of 2seventy bio, Inc.,
4.Registration Statement (Form S-8 No. 333-270660) pertaining to the 2021 Stock Option and Incentive Plan and 2021 Employee Stock Purchase Plan of 2seventy bio, Inc., and
5.Registration Statement (Form S-8 No. 333-276403) pertaining to the 2021 Stock Option and Incentive Plan and 2021 Employee Stock Purchase Plan of 2seventy bio, Inc.

of our report dated March 25, 2025, with respect to the consolidated financial statements of 2seventy bio, Inc. included in this Annual Report (Form 10-K) for the year ended December 31, 2024.


/s/ Ernst & Young LLP


Boston, Massachusetts
March 25, 2025