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Exhibit 23.1

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Consent of Independent Registered Public Accounting Firm

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Checkpoint Therapeutics, Inc.

New York, New York

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We hereby consent to the incorporation by reference in the Registration Statements on Form S­3 (No. 333-251005) and Form S-8 (No. 333-216856, No. 333-221488 and No. 333-251000) of Checkpoint Therapeutics, Inc. of our report dated March 12, 2021, relating to the financial statements which appears in this Annual Report on Form 10-K.

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