Exhibit 31.1

CERTIFICATION

I, Todd C. Brady, certify that:

1. I have reviewed this Amendment No. 1 to the annual report on Form 10-K of Aldeyra Therapeutics, Inc.; and

2. Based on my knowledge, this report does not contain any untrue statements of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.