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We have issued our reports dated March 7, 2025, with respect to the consolidated financial statements and internal control over financial reporting included in the Annual Report of OraSure Technologies, Inc. on Form 10-K for the year ended December 31, 2024. We consent to the incorporation by reference of said reports in the Registration Statements of OraSure Technologies, Inc. on Form S-3 (File No. 333-262633) and on Forms S-8 (File No. 333-281500, File No. 333-273731, File No. 333-270863, File No. 333-270861, File No. 333-248424, File No. 333-220148, File No. 333-198237, File No. 333-176315, File No. 333-151077, File No. 333-138814, File No. 333-118385, File No. 333-102235, and File No. 333-50340).